The publication of DSM-5-TR brings updates to the diagnostic classification and coding of DSM-5 mental disorders, as well as clarifications to the diagnostic criteria for more than 70 disorders. For quick reference, clinicians may find useful this small and convenient manual that contains only the DSM-5-TR Classification (i.e., the complete list of disorders, subtypes, specifiers, and diagnostic codes by DSM-5-TR chapter), an updated section describing use of the manual, and updated DSM-5 diagnostic criteria sets and coding notes. The Desk Reference to the Diagnostic Criteria From DSM-5-TR is meant to be used in conjunction with the fully updated DSM-5-TR. Proper use of the Desk Reference requires familiarity with the text descriptions for each disorder that accompany the criteria sets. The DSM-5-TR text descriptions have also been comprehensively updated to reflect the most recent literature and the impact of culture, racism, and discrimination on psychiatric diagnosis. This handy reference provides all updated ICD-10-CM codes, coding notes, and recording procedures included in DSM-5-TR, including diagnostic criteria for the new diagnosis of prolonged grief disorder. Newly available are also symptom codes for indicating current (and past history of) suicidal behavior and nonsuicidal self-injury. Clinicians will find additional reference informationin DSM-5-TR, including Section III: Emerging Measures and Models (containing assessment measures, updated text on psychiatric diagnosis and culture, cultural formulation and interviews, an alternative DSM-5 model for personality disorders, and conditions for further study) and the DSM-5-TR Appendix (containing alphabetical and numerical ICD-10-CM code listings of DSM-5 diagnoses). Assessment measures and additional information are available online at www.psychiatry.org/dsm5. See www.dsm5.org for periodic DSM-5-TR coding and other updates.